Vol. 6 No. 10 (2026): October
Reimbursement Reviews

Plozasiran (Redemplo)

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Published October 29, 2026

Key Messages

  • Reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
  • The assessments inform nonbinding recommendations that help guide the reimbursement decisions of Canada’s federal, provincial, and territorial governments, with the exception of Quebec.
  • This review assesses plozasiran injection (Redemplo), 25 mg/0.5 mL, sterile solution for subcutaneous use.
  • Indication: As an adjunct to diet to reduce triglyceride levels for adult patients with FCS for whom standard triglyceride-lowering therapies have been inadequate.